![]() Current research studies showed that angiotensin-converting enzyme 2 (ACE2) is expected to be the COVID-19 cell receptor. The spike glycoproteins engage the viral envelope with the targeted cell cytomembrane. The target cell receptor is the key to determining how the virus reaches the cell and which tissues are targeted. The virus morphology is compatible with others in the coronavirus family, particularly SARS-CoV and MERS-CoV. The virus is approximately 125 nm in diameter and is enveloped with spikes (glycoproteins) that are nearly 9 to 12 nm, creating the virus′s coronal form. SARS-CoV-2 viruses (order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae) are mostly spherical, given electron microscopic morphology, although some are polygonal. The novel coronavirus disease (COVID-19) is caused by enveloped RNA viruses (SARS-CoV-2). Conclusion: The people of blood group O may be the least likely to be infected with COVID-19, however, they may be the more in need of treatment in hospital and artificial respiration compared to the other blood groups. The blood group B showed the lowest percentage of patients who experienced myalgia and exhibited the lowest percentage of patients who needed 3 weeks or more to recover. The blood group A showed the lowest percentage of patients who required artificial respiration, whereas the blood group O showed the highest percentage of patients who required artificial respiration. The blood group A showed the highest percentage of patients who experienced an oxygen saturation range of 90–100%, whereas the blood group O showed the highest percentage of patients who experienced an oxygen saturation range of 70–80%. ![]() ![]() There were significant differences among different ABO blood groups regarding the distribution of oxygen saturation percentage, myalgia, and recovery time after COVID-19 infection ( p < 0.01, 0.01, and 0.05, respectively). Results: The subjects with blood group O were the least likely to be infected with the COVID-19 virus, while those with blood group A were not likely to be the most susceptible. The data were collected through two Google Form questionnaires, one for COVID-19 recovered patients (COVID-19 group, n = 726), and the other for the healthy people (Control group, n = 707). Subjects and Methods: This cross-sectional study approached the participants from the Arab community via social media (mainly Facebook and WhatsApp). This study aimed to further confirm the relationship between different blood groups on the vulnerability, symptoms, cure period, and severity among COVID-19 recovered patients. Background and Objectives: Studies have noted that some ABO blood types are more susceptible to COVID-19 virus infection. ![]()
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